Article
Spike Mutation Profiles Associated With SARS-CoV-2 Breakthrough Infections in Delta Emerging and Predominant Time Periods in British Columbia, Canada.
Frontiers in public health - 1 Jan 2022
Fibke Chad D, Joffres Yayuk, Tyson John R, Colijn Caroline, Janjua Naveed Z, Fjell Chris, Prystajecky Natalie, Jassem Agatha, Sbihi Hind
Abstract excerpt
Background: COVID-19 vaccination is a key public health measure in the pandemic response. The rapid evolution of SARS-CoV-2 variants introduce new groups of spike protein mutations. These new mutations are thought to aid in the evasion of vaccine-induced immunity and render vaccines less effective. However, not all spike mutations contribute equally to vaccine escape. Previous studies associate mutations with...
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