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Article

Dominance of Alpha and Iota variants in SARS-CoV-2 vaccine breakthrough infections in New York City.

The Journal of clinical investigation - 15 Sept 2021

Duerr Ralf, Dimartino Dacia, Marier Christian, Zappile Paul, Wang Guiqing, Lighter Jennifer, Elbel Brian, Troxel Andrea B, Heguy Adriana

Abstract excerpt

The efficacy of COVID-19 mRNA vaccines is high, but breakthrough infections still occur. We compared the SARS-CoV-2 genomes of 76 breakthrough cases after full vaccination with BNT162b2 (Pfizer/BioNTech), mRNA-1273 (Moderna), or JNJ-78436735 (Janssen) to unvaccinated controls (February-April 2021) in metropolitan New York, including their phylogenetic relationship, distribution of variants, and full spike...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34375308
DOI: 10.1172/JCI152702
PMCID: PMC8439605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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