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Article

Effects of NCSTN Mutation on Hair Follicle Components in Mice.

Dermatology (Basel, Switzerland) - 1 Jan 2023

Shi Tian-Wei, Cao Wei, Zhao Qing-Zan, Yu Hong-Xing, Zhang Si-Sen, Hao Yi-Bin

Abstract excerpt

BACKGROUND AND OBJECTIVES: Hidradenitis suppurativa (HS)/acne inversa is an intractable skin disease that is characterized by destructive lesions - primarily on the flexural areas. Although its etiology is unknown, genetics is considered to be a factor of its pathology - mutations in γ-secretase genes have been identified in certain familial HS patients, and follicular occlusion is widely accepted as the primary...

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PMID: 35843211
DOI: 10.1159/000525526

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