Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Morules But Not Squamous Differentiation are a Reliable Indicator of CTNNB1 (β-catenin) Mutations in Endometrial Carcinoma and Precancers.

The American journal of surgical pathology - 1 Oct 2022

Niu Shuang, Lucas Elena, Molberg Kyle, Strickland Amanda, Wang Yan, Carrick Kelley, Rivera-Colon Glorimar, Gwin Katja, SoRelle Jeffrey A, Castrillon Diego H, Zheng Wenxin, Chen Hao

Abstract excerpt

Although collectively regarded as "squamous differentiation (SD)" in endometrial endometrioid carcinoma (EEC) and atypical hyperplasia/endometrioid intraepithelial neoplasia (AH/EIN), morules (often referred to as "squamous morules") and true SD may represent two distinct phenomena. Here, we explored the distinction between morules versus SD and investigated the association of morules and SD with CTNNB1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

Share to Immunohistochemistry

Share to Mutation

Source

Identifiers

PMID: 35834400
DOI: 10.1097/PAS.0000000000001934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Morules But Not Squamous Differentiation are a Reliable Indicator of CTNNB1 (β-catenin) Mutations in Endometrial Carcinoma and Precancers.PMID 35834400Read ↗

Distinct molecular alterations in complex endometrial hyperplasia (CEH) with and without immature squamous metaplasia (squamous morules).Semantic proximity Read ↗

Squamous morules are functionally inert elements of premalignant endometrial neoplasia.Semantic proximity Read ↗

Morules and β-catenin predict POLE mutation status in endometrial cancer: A pathway to more cost-effective diagnostic procedures.Semantic proximity Read ↗

Relationship between morular metaplasia and squamous differentiation in endometrial carcinoma.Semantic proximity Read ↗

Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are UncommonSemantic proximity Read ↗

Hypermethylated PCDHGB7 as a Biomarker for Early Detection of Endometrial Cancer in Endometrial Brush Samples and Cervical ScrapingsSemantic proximity Read ↗

Molecular Subtype and Mutational Profile of Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia.Semantic proximity Read ↗

Mechanisms of mutant β-catenin in endometrial cancer progressionSemantic proximity Read ↗

Morules and morule-like features associated with carcinomas in various organs: report with immunohistochemical and molecular studies.Semantic proximity Read ↗

Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation.Semantic proximity Read ↗

Ovarian cancer detection by DNA methylation in cervical scrapingsSemantic proximity Read ↗

Diagnosis of premalignant endometrial disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.