Article
Within-host evolution of a gut pathobiont facilitates liver translocation.
Nature - 1 Jul 2022
Yang Yi, Nguyen Mytien, Khetrapal Varnica, Sonnert Nicole D, Martin Anjelica L, Chen Haiwei, Kriegel Martin A, Palm Noah W
Abstract excerpt
Gut commensal bacteria with the ability to translocate across the intestinal barrier can drive the development of diverse immune-mediated diseases1-4. However, the key factors that dictate bacterial translocation remain unclear. Recent studies have revealed that gut microbiota strains can adapt and evolve throughout the lifetime of the host5-9, raising the possibility that changes in individual commensal bacteria...
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