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Article

Pancreatic mixed acinar-neuroendocrine carcinoma in a patient with a germline BRCA2 mutation: a case report.

Clinical journal of gastroenterology - 1 Oct 2022

Ikeda Mio, Miura Shin, Kume Kiyoshi, Kikuta Kazuhiro, Hamada Shin, Takikawa Tetsuya, Nakagawa Kei, Unno Michiaki, Furukawa Toru, Masamune Atsushi

Abstract excerpt

Loss of function in the BRCA2 gene exacerbates ovarian, breast, and pancreatic ductal cancer risk. Despite being implicated in the pancreatic ductal epithelium carcinogenesis, the involvement of a germline BRCA2 mutation in acinar and endocrine cells is less reported. A 45-year-old woman with a history of breast cancer was referred to our hospital for a detailed examination of epigastric pain. Her father had...

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PMID: 35819745
DOI: 10.1007/s12328-022-01668-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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