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Strain Specific Variations in Acinetobacter baumannii Complement Sensitivity

22 Jun 2022

Abstract excerpt

The complement system is required for innate immunity against Acinetobacter baumannii, an important cause of antibiotic resistant systemic infections. A. baumannii strains differ in their susceptibility to the membrane attack complex (MAC) formed from terminal complement pathway proteins, but the reasons for this variation remain poorly understood. We have characterized in detail the complement sensitivity...

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PMID: 35812377
DOI: 10.3389/fimmu.2022.853690

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