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Article

The Role of Polymorphisms at the Interleukin-1, Interleukin-4, GATA-3 and Cyclooxygenase-2 Genes in Non-Surgical Periodontal Therapy.

International journal of molecular sciences - 30 Jun 2022

Walther Kay-Arne, Gonzales José Roberto, Gröger Sabine, Ehmke Benjamin, Kaner Dogan, Lorenz Katrin, Eickholz Peter, Kocher Thomas, Kim Ti-Sun, Schlagenhauf Ulrich, Koch Raphael, Meyle Jörg

Abstract excerpt

Periodontitis is a multifactorial disease. The aim of this explorative study was to investigate the role of Interleukin-(IL)-1, IL-4, GATA-3 and Cyclooxygenase-(COX)-2 polymorphisms after non-surgical periodontal therapy with adjunctive systemic antibiotics (amoxicillin/metronidazole) and subsequent maintenance in a Caucasian population. Analyses were performed using blood samples from periodontitis patients of a...

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Identifiers

PMID: 35806269
DOI: 10.3390/ijms23137266
PMCID: PMC9266438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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