Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Utilization of AlphaFold2 to Predict MFS Protein Conformations after Selective Mutation.

International journal of molecular sciences - 29 Jun 2022

Xiao Qingjie, Xu Mengxue, Wang Weiwei, Wu Tingting, Zhang Weizhe, Qin Wenming, Sun Bo

Abstract excerpt

The major facilitator superfamily (MFS) is the largest secondary transporter family and is responsible for transporting a broad range of substrates across the biomembrane. These proteins are involved in a series of conformational changes during substrate transport. To decipher the transport mechanism, it is necessary to obtain structures of these different conformations. At present, great progress has been made...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crystallography, X-Ray
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Transport Proteins

Share to Models, Molecular

Share to Mutation

Share to Protein Conformation

Source

Open in PubMed Open full text

Identifiers

PMID: 35806248
DOI: 10.3390/ijms23137235
PMCID: PMC9266783

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Utilization of AlphaFold2 to Predict MFS Protein Conformations after Selective Mutation.PMID 35806248Read ↗

Integration of AlphaFold with Molecular Dynamics for Efficient Conformational Sampling of Transporter Protein NarK.Semantic proximity Read ↗

MoDAFold: a strategy for predicting the structure of missense mutant protein based on AlphaFold2 and molecular dynamics.Semantic proximity Read ↗

Protein multiple conformations prediction using multi-objective evolution algorithmSemantic proximity Read ↗

AFsample2: Predicting multiple conformations and ensembles with AlphaFold2Semantic proximity Read ↗

Comprehensive Collection and Prediction of ABC Transmembrane Protein Structures in the AI Era of Structural BiologySemantic proximity Read ↗

Comprehensive collection and prediction of ABC transmembrane protein structures in the AI era of structural biologySemantic proximity Read ↗

Structure Bioinformatics of Eight Human ATP Synthase Fo Subunits and Their AlphaFold3-Predicted Water-Soluble QTY AnalogsSemantic proximity Read ↗

Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2.Semantic proximity Read ↗

Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering.Semantic proximity Read ↗

Predicting multiple conformations via sequence clustering and AlphaFold2.Semantic proximity Read ↗

Confrontation of AlphaFold2 models with cryo-EM and crystal structures enlightens alternate geometries of the CYP102A1 multidomain proteinSemantic proximity Read ↗

The FoldX web server: an online force field.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.