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Article

Identifying intragenic functional modules of genomic variations associated with cancer phenotypes by learning representation of association networks.

BMC medical genomics - 6 Jul 2022

Kim Minsu, Huffman Jennifer E, Justice Amy, Goethert Ian, Agasthya Greeshma, Danciu Ioana

Abstract excerpt

BACKGROUND: Genome-wide Association Studies (GWAS) aims to uncover the link between genomic variation and phenotype. They have been actively applied in cancer biology to investigate associations between variations and cancer phenotypes, such as susceptibility to certain types of cancer and predisposed responsiveness to specific treatments. Since GWAS primarily focuses on finding associations between individual...

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PMID: 35794577
DOI: 10.1186/s12920-022-01298-6
PMCID: PMC9258200

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