Article
Genetic diversity and spatial distribution of Burkholderia mallei by core genome-based multilocus sequence typing analysis.
PloS one - 1 Jan 2022
Appelt Sandra, Rohleder Anna-Maria, Jacob Daniela, von Buttlar Heiner, Georgi Enrico, Mueller Katharina, Wernery Ulrich, Kinne Joerg, Joseph Marina, Jose Shantymol V, Scholz Holger C
Abstract excerpt
Burkholderia mallei is the etiological agent of glanders, a highly contagious and often fatal disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing assays are necessary to differentiate between individual strains. Here we report on the development and validation of a robust and reproducible core genome-based Multi Locus Sequence Typing Assay (cgMLST) for B. mallei, which is...
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