Article
Tandem repeat regions within the Burkholderia pseudomallei genome and their application for high resolution genotyping.
BMC microbiology - 30 Mar 2007
U'Ren Jana M, Schupp James M, Pearson Talima, Hornstra Heidie, Friedman Christine L Clark, Smith Kimothy L, Daugherty Rebecca R Leadem, Rhoton Shane D, Leadem Ben, Georgia Shalamar, Cardon Michelle, Huynh Lynn Y, DeShazer David, Harvey Steven P, Robison Richard, Gal Daniel, Mayo Mark J, Wagner David, Currie Bart J, Keim Paul
Abstract excerpt
BACKGROUND: The facultative, intracellular bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a serious infectious disease of humans and animals. We identified and categorized tandem repeat arrays and their distribution throughout the genome of B. pseudomallei strain K96243 in order to develop a genetic typing method for B. pseudomallei. We then screened 104 of the potentially polymorphic...
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