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Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis (review).

Molecular medicine reports - 1 May 2014

Kobayashi Hiroshi, Imanaka Shogo, Nakamura Haruki, Tsuji Ayumi

Abstract excerpt

Endometriosis is a complex disease influenced by genetic, epigenetic and environmental factors. The aim of the present study was to describe genomic instability, genetic polymorphisms and their haplotype, epigenetic alterations associated with predisposition to endometriosis, and the key factors associated with endometriosis-related ovarian neoplasms. Focus has been given on the developing paradigm that...

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Cell Transformation, Neoplastic
DNA, Mitochondrial
Endometriosis
Epigenesis, Genetic
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genomic Instability

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PMID: 24639062
DOI: 10.3892/mmr.2014.2057

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