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Article

PHF5A Contributes to the Maintenance of the Cancer Stem-like Phenotype in Non-Small Cell Lung Cancer by Regulating Histone Deacetylase 8.

Annals of clinical and laboratory science - 1 May 2022

Yang Yan, Li Man, Zhou Xueli, Wang Wei, Shao Yu, Yao Jinghao, Wang Xiaojing

Abstract excerpt

OBJECTIVE: Cancer stem-like cells (CSLCs) are closely associated with tumor recurrence, metastasis, and drug-resistance. PHD-finger domain protein 5A (PHF5A) is related to tumorigenesis and development of non-small cell lung cancer (NSCLC). The role and regulatory mechanism of PHF5A in CSLCs of NSCLC remain unclear. This study aimed to identify the biological characteristics of CSLCs and the role of PHF5A in...

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PMID: 35777798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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