Article
SETD8 is a prognostic biomarker that contributes to stem-like cell properties in non-small cell lung cancer.
Pathology, research and practice - 1 Dec 2020
Piao Lihua, Feng Ying, Che Nan, Li Mengxuan, Li Xiaogang, Jin Yu, Xuan Yanhua
Abstract excerpt
SETD8 is a lysine methyltransferase containing an SET domain and has been reported to regulate various biological processes, including carcinogenesis. However, its prognostic value and mechanisms of action in non-small cell lung cancer (NSCLC) have not been extensively studied. Here, we assessed SETD8 expression and its relationship with clinicopathological parameters, cancer stemness proteins, and cell...
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