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Article

Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue

24 Jun 2022

Abstract excerpt

Metabolic plasticity is the ability of a biological system to adapt its metabolic phenotype to different environmental stressors. We used a whole-body and tissue-specific phenotypic, functional, proteomic, metabolomic and transcriptomic approach to systematically assess metabolic plasticity in diet-induced obese mice after a combined nutritional and exercise intervention. Although most obesity and...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 35777200
DOI: 10.1016/j.redox.2022.102353

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