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Article

Candida auris Pan-Drug-Resistant to Four Classes of Antifungal Agents

30 Jun 2022

Abstract excerpt

mutations, four amphotericin B-resistant isolates showed no distinct nonsynonymous variants suggesting unknown genetic elements driving the resistance. Pan-drug-resistant C. auris isolates were not susceptible to two-drug antifungal combinations tested by checkerboard, Etest, and time-kill methods. The fungal population pattern, discerned from SNP phylogenetic analysis, was consistent with in-hospital or...

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PMID: 35770999
DOI: 10.1128/aac.00053-22

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