Article
Distribution of celiac disease predisposing genes HLA-DQ2 and HLA-DQ8 in the native population of southern India.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Jun 2022
Verma Anil K, Mechenro John, Monachesi Chiara, Venugopal Giriprasad, Catassi Giulia Naspi, Lionetti Elena, Ramakrishna Balakrishnan S, Catassi Carlo
Abstract excerpt
BACKGROUND: Celiac disease (CD) is an intestinal inflammatory condition caused by the ingestion of gluten peptides in wheat and related grains in individuals carrying HLA-DQ2 and/or HLA-DQ8 genes. In comparison to HLA-DQ8, a higher HLA-DQ2 prevalence is reported in European population where wheat has been the staple food for thousands of years. In non-European population, this pattern of HLA-DQ CD-predisposing...
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