Article
A new deep learning technique reveals the exclusive functional contributions of individual cancer mutations.
The Journal of biological chemistry - 1 Aug 2022
Gupta Prashant, Jindal Aashi, Ahuja Gaurav, Jayadeva, Sengupta Debarka
Abstract excerpt
Cancers are caused by genomic alterations that may be inherited, induced by environmental carcinogens, or caused due to random replication errors. Postinduction of carcinogenicity, mutations further propagate and drastically alter the cancer genomes. Although a subset of driver mutations has been identified and characterized to date, most cancer-related somatic mutations are indistinguishable from germline...
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