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Article

Genetic testing to guide screening for pancreatic ductal adenocarcinoma: Results of a microsimulation model.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Sept 2022

Peters Mary Linton B, Eckel Andrew, Lietz Anna, Seguin Claudia, Mueller Peter, Hur Chin, Pandharipande Pari V

Abstract excerpt

BACKGROUND: First-degree relatives (FDRs) of patients with pancreatic ductal adenocarcinoma (PDAC) have elevated PDAC risk, partially due to germline genetic variants. We evaluated the potential effectiveness of genetic testing to target MRI-based screening among FDRs. METHODS: We used a microsimulation model of PDAC, calibrated to Surveillance, Epidemiology, and End Results (SEER) data, to estimate the potential...

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Identifiers

PMID: 35752568
DOI: 10.1016/j.pan.2022.05.003
PMCID: PMC9474673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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