Article
Cost-effectiveness of alternating magnetic resonance imaging and digital mammography screening in BRCA1 and BRCA2 gene mutation carriers.
Cancer - 15 Mar 2013
Cott Chubiz Jessica E, Lee Janie M, Gilmore Michael E, Kong Chung Y, Lowry Kathryn P, Halpern Elkan F, McMahon Pamela M, Ryan Paula D, Gazelle G Scott
Abstract excerpt
BACKGROUND: Current clinical guidelines recommend earlier, more intensive breast cancer screening with both magnetic resonance imaging (MRI) and mammography for women with breast cancer susceptibility gene (BRCA) mutations. Unspecified details of screening schedules are a challenge for implementing guidelines. METHODS: A Markov Monte Carlo computer model was used to simulate screening in asymptomatic women who...
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