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Article

MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus

1 Jul 2022

Abstract excerpt

Abstract Our recent data demonstrate a critical role of the RIG-I–like receptor family in regulating antifungal immunity against Aspergillus fumigatus in a murine model. However, the importance of this pathway in humans and the cell types that use this innate immune receptor family to detect A. fumigatus remain unresolved. In this study, using patients who underwent hematopoietic stem cell transplantation, we...

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PMID: 35750336
DOI: 10.4049/jimmunol.2100759

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