Article
Incidental discovery of acute myeloid leukemia during liquid biopsy of a lung cancer patient.
Cold Spring Harbor molecular case studies - 1 Jun 2022
Nkosi Dingani, Miller Caroline A, Jajosky Audrey N, Oltvai Zoltán N
Abstract excerpt
Liquid biopsy is considered an alternative to standard next-generation sequencing (NGS) of solid tumor samples when biopsy tissue is inadequate for testing or when testing of a peripheral blood sample is preferred. A common assumption of liquid biopsies is that the NGS data obtained on circulating cell-free DNA is a high-fidelity reflection of what would be found by solid tumor testing. Here, we describe a case...
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