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Article

Effects of glycemic traits on left ventricular structure and function: a mendelian randomization study.

Cardiovascular diabetology - 17 Jun 2022

Ai Sizhi, Wang Xiaoyu, Wang Shanshan, Zhao Yilin, Guo Shuxun, Li Guohua, Chen Zhigang, Lin Fei, Guo Sheng, Li Yan, Zhang Jihui, Zhao Guoan

Abstract excerpt

BACKGROUND: Adverse ventricular structure and function is a key pathogenic mechanism of heart failure. Observational studies have shown that both insulin resistance (IR) and glycemic level are associated with adverse ventricular structure and function. However, whether IR and glycemic level are causally associated with cardiac structure and function remains unclear. METHODS: Genetic variants for IR, fasting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35715813
DOI: 10.1186/s12933-022-01540-6
PMCID: PMC9206364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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