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Utility and implications of exome sequencing in early‐onset Parkinson's disease

10 Dec 2018

Abstract excerpt

BACKGROUND: Although the genetic load is high in early-onset Parkinson's disease, thorough investigation of the genetic diagnostic yield has yet to be established. The objectives of this study were to assess variants in known genes for PD and other movement disorders and to find new candidates in 50 patients with early-onset PD. METHODS: We searched for variants either within genes listed by the International...

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PMID: 30537300
DOI: 10.1002/mds.27559

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