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Article

Prediction and expression analysis of deleterious nonsynonymous SNPs of Arabidopsis ACD11 gene by combining computational algorithms and molecular docking approach.

PLoS computational biology - 1 Jun 2022

Rifat Mahmudul Hasan, Ahmed Jamil, Ahmed Milad, Ahmed Foeaz, Gulshan Airin, Hasan Mahmudul

Abstract excerpt

Accelerated cell death 11 (ACD11) is an autoimmune gene that suppresses pathogen infection in plants by preventing plant cells from becoming infected by any pathogen. This gene is widely known for growth inhibition, premature leaf chlorosis, and defense-related programmed cell death (PCD) in seedlings before flowering in Arabidopsis plant. Specific amino acid changes in the ACD11 protein's highly conserved...

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PMID: 35709304
DOI: 10.1371/journal.pcbi.1009539
PMCID: PMC9242461

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