Article
Knockout of Arabidopsis accelerated-cell-death11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense.
Genes & development - 15 Feb 2002
Brodersen Peter, Petersen Morten, Pike Helen M, Olszak Brian, Skov Søren, Odum Niels, Jørgensen Lise Bolt, Brown Rhoderick E, Mundy John
Abstract excerpt
We describe the lethal, recessive accelerated-cell-death11 Arabidopsis mutant (acd11). Cell death in acd11 exhibits characteristics of animal apoptosis monitored by flow cytometry, and acd11 constitutively expresses defense-related genes that accompany the hypersensitive response normally triggered by avirulent pathogens. Global transcriptional changes during programmed cell death (PCD) and defense activation in...
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