Article
Prognostic Impact and Phenotype of Residual Acute Myeloid Leukemia Stem Cells.
Clinical laboratory - 1 Jun 2022
Jaddaoui Samiha, Bencharef Hanaa, Lamchahab Mouna, Quessar Asmaa, Oukkache Bouchra
Abstract excerpt
BACKGROUND: Leukemia stem cells (LSCs) have been demonstrated to be more therapy-resistant than leukemic blast cells reflecting measurable residual disease (MRD). CD34+CD38- cell frequency is an independent factor for relapse prediction and could therefore be used in the future to improve MRD assessment in acute myeloid leukemia (AML). This protocol is designed to enable accurate and reproducible immunophenotypic...
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