Article
The Use of Pro-Angiogenic and/or Pro-Hypoxic miRNAs as Tools to Monitor Patients with Diffuse Gliomas.
International journal of molecular sciences - 27 May 2022
Levallet Guénaëlle, Dubois Fatéméh, Leclerc Arthur, Petit Edwige, Bekaert Lien, Faisant Maxime, Creveuil Christian, Emery Evelyne, Zalcman Gérard, Lechapt-Zalcman Emmanuèle
Abstract excerpt
IDH (isocitrate dehydrogenase) mutation, hypoxia, and neo-angiogenesis, three hallmarks of diffuse gliomas, modulate the expression of small non-coding RNAs (miRNA). In this paper, we tested whether pro-angiogenic and/or pro-hypoxic miRNAs could be used to monitor patients with glioma. The miRNAs were extracted from tumoral surgical specimens embedded in the paraffin of 97 patients with diffuse gliomas and, for 7...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
