Adoptive immunotherapy overcomes genetic susceptibility to bloodstream infections due to fc-gamma receptor polymorphisms after liver transplantation.

doi:10.1111/ajt.17113

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Article

Adoptive immunotherapy overcomes genetic susceptibility to bloodstream infections due to fc-gamma receptor polymorphisms after liver transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Oct 2022

Shimizu Seiichi, Ohira Masahiro, Tanaka Yuka, Ide Kentaro, Tahara Hiroyuki, Kuroda Shintaro, Tanimine Naoki, Doskali Marlen, Hotta Ryuichi, Yano Takuya, Nakano Ryosuke, Imaoka Yuki, Sato Koki, Imaoka Kouki, Kobayashi Tsuyoshi, Ohdan Hideki

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in FCGR3A can predict the susceptibility of liver transplant (LT) recipients to bloodstream infections (BSI) and clinical outcomes following living-donor LT (LDLT). Here, we retrospectively analyzed the relationship of adoptive immunotherapy with activated natural killer (NK) cells from perfusate effluents of liver allografts against BSI following LDLT. Higher BSI incidence...

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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35670552
DOI: 10.1111/ajt.17113

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