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Article

Generation of a human iPSC line (MPIi007-A) from a patient with Metachromatic leukodystrophy.

Stem cell research - 1 Oct 2020

Kim Kee-Pyo, Yoon Juyong, Kim Johnny, Röpke Albrecht, Shin Borami, Wook Han Dong, Greber Boris, Schöler Hans R

Abstract excerpt

Here we have generated a human induced pluripotent stem cells (hiPSC) line (MPIi007-A) from skin fibroblasts of a 4-year-old male Metachromatic leukodystrophy (MLD) patient with a heterozygous 1178C > G (Thr393Ser) mutation in arylsulfatase A (ARSA) gene via retroviral expression of OCT4, SOX2, KLF4 and c-MYC. The MPIi007-A iPSC line displayed typical embryonic stem cell-like morphology, carried the ARSA gene...

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Identifiers

PMID: 32950023
DOI: 10.1016/j.scr.2020.101993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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