Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The risks of RELN polymorphisms and its expression in the development of otosclerosis.

PloS one - 1 Jan 2022

Priyadarshi Saurabh, Hansdah Kirtal, Singh Neha, Bouzid Amal, Ray Chinmay Sundar, Panda Khirod Chandra, Biswal Narayan Chandra, Desai Ashim, Choudhury Jyotish Chandra, Tekari Adel, Masmoudi Saber, Ramchander Puppala Venkat

Abstract excerpt

Otosclerosis (OTSC) is the primary form of conductive hearing loss characterized by abnormal bone remodelling within the otic capsule of the human middle ear. A genetic association of the RELN SNP rs3914132 with OTSC has been identified in European population. Previously, we showed a trend towards association of this polymorphism with OTSC and identified a rare variant rs74503667 in a familial case. Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease
Share to Genotype
Share to Otosclerosis
Share to Polymorphism, Single Nucleotide
Share to Reelin Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 35658052
DOI: 10.1371/journal.pone.0269558
PMCID: PMC9165908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The risks of RELN polymorphisms and its expression in the development of otosclerosis.PMID 35658052Read ↗

Genetic variants in RELN are associated with otosclerosis in a non-European population from Tunisia.Semantic proximity Read ↗

A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis.Semantic proximity Read ↗

Lack of association between SNP rs3914132 of the RELN gene and otosclerosis in India.Semantic proximity Read ↗

Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure.Semantic proximity Read ↗

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal StructureSemantic proximity Read ↗

The rs39335 polymorphism of the RELN gene is not associated with otosclerosis in a southern Italian population.Semantic proximity Read ↗

Genetic variants in the RELN gene are associated with otosclerosis in multiple European populations.Semantic proximity Read ↗

Osteoprotegerin gene polymorphisms and otosclerosis: an additional genetic association study, multilocus interaction and meta-analysis.Semantic proximity Read ↗

Evidence of distinct RELN and TGFB1 genetic associations in familial and non-familial otosclerosis in a British population.Semantic proximity Read ↗

Genetic variants and altered expression of SERPINF1 confer disease susceptibility in patients with otosclerosis.Semantic proximity Read ↗

A new locus for otosclerosis, OTSC8, maps to the pericentromeric region of chromosome 9.Semantic proximity Read ↗

Osteoprotegerin gene polymorphisms and otosclerosis: an additional genetic association study, multilocus interaction and meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.