Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulation of the CD147 complex confers defective placental development: A pathogenesis of early‐onset preeclampsia

1 Jun 2022

Abstract excerpt

Dear Editor, Trophoblastic CD147, also known as basigin (BSG), regulates the differentiation and spiral artery remodelling functions of extravillous trophoblasts (EVCTs), and its deficiency contributes to the pathophysiology of preeclampsia (PE). The biological activities of CD147 are mediated by its interaction with integrin β1 and Wnt/β-catenin signalling. The reduced serum and villous CD147 levels in PE are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Issues in Pregnancy
Share to Maternal and fetal healthcare
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35653421
DOI: 10.1002/ctm2.826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of the CD147 complex confers defective placental development: A pathogenesis of early‐onset preeclampsiaPMID 35653421Read ↗

Human Placenta and Evolving Insights into Pathological Changes of Preeclampsia: A Comprehensive Review of the Last DecadeSemantic proximity Read ↗

Overview of extracellular vesicles in the pathogenesis of preeclampsiaSemantic proximity Read ↗

CLDN1 regulates trophoblast apoptosis and proliferation in preeclampsiaSemantic proximity Read ↗

Translational Analysis of Mouse and Human Placental Protein and mRNA Reveals Distinct Molecular Pathologies in Human PreeclampsiaSemantic proximity Read ↗

Upregulation of Siglec-6 induces mitochondrial dysfunction by promoting GPR20 expression in early-onset preeclampsiaSemantic proximity Read ↗

ITGB3 is reduced in pregnancies with preeclampsia and its influence on biological behavior of trophoblast cellsSemantic proximity Read ↗

VGLL3-centered network connects placental, vascular, and immune defects in preeclampsiaSemantic proximity Read ↗

Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth – SYDE1 regulates placental cell migration and invasionSemantic proximity Read ↗

MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of PreeclampsiaSemantic proximity Read ↗

Proteoglycans: Systems-Level Insight into Their Expression in Healthy and Diseased PlacentasSemantic proximity Read ↗

BCAM Deficiency May Contribute to Preeclampsia by Suppressing the PIK3R6/p-STAT3 SignalingSemantic proximity Read ↗

Human Trophoblast Cell-Derived Extracellular Vesicles Facilitate Preeclampsia by Transmitting miR-1273d, miR-4492, and miR-4417 to Target HLA-GSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.