Article
Germline Abnormalities in DNA Methylation and Histone Modification and Associated Cancer Risk.
Current hematologic malignancy reports - 1 Aug 2022
Fernandez Jenna A, Patnaik Mrinal M
Abstract excerpt
PURPOSE OF REVIEW: Somatic mutations in DNA methyltransferases and other DNA methylation associated genes have been found in a wide variety of cancers. Germline mutations in these genes have been associated with several rare hereditary disorders. Among the described germline/congenital disorders, neurological dysfunction and/or growth abnormalities appear to be a common phenotype. Here, we outline known germline...
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