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Article

BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.

Frontiers in endocrinology - 1 Jan 2022

Gao Yuan, Xiang Dapeng, Li Weijie, Zheng Xi, Wang Lin, Li Zhiyu, Chen Ting

Abstract excerpt

BRAF mutation accounts for 50% of the PTC (papillary thyroid carcinoma) and is closely associated with high-risk clinicopathological characteristics. Increasing evidence implied that dysregulation of miRNA participated in carcinogenesis and progression of cancer. Clinical data showed the significant up-regulation of miR-222-3p in PTC; however, the role of miR-222-3p and possible relationship with BRAF mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 35651980
DOI: 10.3389/fendo.2022.843334
PMCID: PMC9148970

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