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Article

Collagenase Clostridium Histolyticum-aaes for Treatment of Cellulite: A Pooled Analysis of Two Phase-3 Trials

1 May 2022

Abstract excerpt

Background: Collagen-rich fibrous septae and subcutaneous adipose protrusions play a role in cellulite pathophysiology. Collagenase clostridium histolyticum-aaes (CCH-aaes) injection causes enzymatic release of septae to resolve cellulite depressions and create a skin smoothing effect. This analysis pooled data from two identically designed, phase-3, randomized, double-blind, placebo-controlled studies to examine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35646496
DOI: 10.1097/gox.0000000000004306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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