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Article

Association study identifies genetic determinants and non-genetic factors on steady-state plasma and therapeutic outcome of galantamine in mixed dementia.

European journal of clinical pharmacology - 1 Aug 2022

Yaowaluk Thitipon, Senanarong Vorapun, Limwongse Chanin, Boonprasert Rasda, Bunditvorapoom Duangkamon, Kaewsutthi Supannee, Kijsanayotin Pornpimol

Abstract excerpt

PURPOSE: This study aimed to evaluate the influence of genetic polymorphisms of drug-metabolizing enzyme genes, transporter gene, pathological gene (APOE), and non-genetic factors on therapeutic outcomes as well as steady-state plasma concentrations (Cpss) of galantamine in Thai patients with mixed dementia. METHODS: Fifty-one Thai patients with mixed dementia who received galantamine for at least 6 months were...

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PMID: 35633386
DOI: 10.1007/s00228-022-03322-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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