Article
Differential Expression of Proteins in an Atypical Presentation of Autoimmune Lymphoproliferative Syndrome.
International journal of molecular sciences - 11 May 2022
Delgadillo Dulce María, Céspedes-Cruz Adriana Ivonne, Ríos-Castro Emmanuel, Rodríguez Maldonado María Guadalupe, López-Nogueda Mariel, Márquez-Gutiérrez Miguel, Villalobos-Manzo Rocío, Ramírez-Reyes Lorena, Domínguez-Fuentes Misael, Tapia-Ramírez José
Abstract excerpt
Autoimmune lymphoproliferative syndrome (ALPS) is a rare disease defined as a defect in the lymphocyte apoptotic pathway. Currently, the diagnosis of ALPS is based on clinical aspects, defective lymphocyte apoptosis and mutations in Fas, FasL and Casp 10 genes. Despite this, ALPS has been misdiagnosed. The aim of this work was to go one step further in the knowledge of the disease, through a molecular and...
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