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Loricrin at the Boundary between Inside and Outside

6 May 2022

Abstract excerpt

Cornification is a specialized mode of the cell-death program exclusively allowed for terrestrial amniotes. Recent investigations suggest that loricrin (LOR) is an important cornification effector. As the connotation of its name ("lorica" meaning an armor in Latin) suggests, the keratin-associated protein LOR promotes the maturation of the epidermal structure through organizing covalent cross-linkages, endowing...

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PMID: 35625601
DOI: 10.3390/biom12050673

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