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Hair Follicle-Related MicroRNA-34a Serum Expression and rs2666433A/G Variant in Patients with Alopecia: A Cross-Sectional Analysis.

Biomolecules - 19 Apr 2022

Maher Shymaa Ahmed, Ismail Nader Ali, Toraih Eman A, Habib Alaa H, Gouda Nawal S, Gomaa Amal H A, Fawzy Manal S, Helal Ghada M

Abstract excerpt

Alopecia areata (AA) is a type of immune-mediated alopecia. Recent studies have suggested microRNAs’ (miRNAs) implication in several cellular processes, including epidermal and hair follicle biology. Single nucleotide polymorphisms (SNPs) can modify gene expression levels, which may induce an autoimmune response. This case−control study included 480 participants (240 for each case/control group). MicroRNA-34a...

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Alopecia Areata
Case-Control Studies
Cross-Sectional Studies
Genetic Predisposition to Disease
Hair Follicle

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PMID: 35625530
DOI: 10.3390/biom12050602
PMCID: PMC9138785

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