Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically predicted physical activity is associated with lower serum urate concentrations.

Genes & genomics - 1 Jul 2022

Guan Ying, Wei Jiahe, Meng Lifeng, Li Yasong, Wang Tianle, Chen Dingwan, Qian Qilin

Abstract excerpt

BACKGROUND: Physical activity (PA) is considered to play an important role in the reduced gout risk. However, the epidemiology results are inconsistent and causality remains unclear. OBJECTIVE: To investigate the causal relationship of PA with serum urate concentrations and gout risk by a bidirectional Mendelian randomization (MR) approach. METHOD: Two genome-wide association studies (GWASs) from UK Biobank were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exercise
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Uric Acid

Source

Identifiers

PMID: 35622233
DOI: 10.1007/s13258-022-01239-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically predicted physical activity is associated with lower serum urate concentrations.PMID 35622233Read ↗

The Impact of Different Intensities of Physical Activity on Serum Urate and Gout: A Mendelian Randomization StudySemantic proximity Read ↗

Physical activity, sedentary behavior, and the risk of type 2 diabetes: A two-sample Mendelian Randomization analysis in the European population.Semantic proximity Read ↗

Using multiple Mendelian randomization approaches and genetic correlations to understand obesity, urate, and gout.Semantic proximity Read ↗

Causal Relationships Between Total Physical Activity and Ankylosing Spondylitis: A Mendelian Randomization Study.Semantic proximity Read ↗

Investigating Casual Associations Among Physical Activity, Gut Microbiota and Cancers: A Mendelian Randomization StudySemantic proximity Read ↗

Physical activity and risk of gallstone disease: A Mendelian randomization studySemantic proximity Read ↗

Association of Sedentary and Physical Activity Behaviors with Body Composition: a Genome-Wide Association and Mendelian Randomization StudySemantic proximity Read ↗

Accelerometer-Derived and Genetically Inferred Physical Activity and Human DiseaseSemantic proximity Read ↗

Genetic susceptibility, walking activity and the risk of incident gout.Semantic proximity Read ↗

Causal association of physical activity with low back pain, intervertebral disc degeneration and sciatica: a two-sample mendelian randomization analysis studySemantic proximity Read ↗

Assessing causality between osteoarthritis with urate levels and gout: a bidirectional Mendelian randomization study.Semantic proximity Read ↗

Genetically predicted serum uric acid and pulmonary arterial hypertension: Mendelian randomization with an exploratory NHANES risk-burden analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.