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Article

Omicron variant receptor-binding domain phylogenetics and molecular dynamics.

Computers in biology and medicine - 1 Jul 2022

Kandeel Mahmoud, El-Deeb Wael

Abstract excerpt

BACKGROUND: We investigated the evolutionary relationships, mutations, antigenic epitopes, and structural dynamics of the receptor-binding domain (RBD) of SARS-CoV-2, Omicron and other recently evolved variants. METHODS: The RBD of SARS-CoV-2 and its Omicron, Alpha, Beta, Gamma, Delta, and Mu variants were subjected to pairwise sequence matrix evaluation, antigenic epitope prediction, and phylogenetic...

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Identifiers

PMID: 35605487
DOI: 10.1016/j.compbiomed.2022.105633
PMCID: PMC9110309

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