Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Electrical responses from human retinal cone pathways associate with a common genetic polymorphism implicated in myopia

20 May 2022

Abstract excerpt

Myopia is the commonest visual impairment. Several genetic loci confer risk, but mechanisms by which they do this are unknown. Retinal signals drive eye growth, and myopia usually results from an excessively long eye. The common variant most strongly associated with myopia is near the GJD2 gene, encoding connexin-36, which forms retinal gap junctions. Light-evoked responses of retinal neurons can be recorded...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ophthalmology and Visual Impairment Studies
Share to Retinal Development and Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35594404
DOI: 10.1073/pnas.2119675119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Electrical responses from human retinal cone pathways associate with a common genetic polymorphism implicated in myopiaPMID 35594404Read ↗

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism.Semantic proximity Read ↗

Genetic Spectrum of Negative Electroretinograms in a Predominantly Pediatric Cohort of 177 Patients.Semantic proximity Read ↗

Electronegative electroretinography in inherited retinal disease: a systematic review of genotype-phenotype correlations.Semantic proximity Read ↗

Natural history and biomarkers of KCNV2-associated retinopathy.Semantic proximity Read ↗

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.Semantic proximity Read ↗

KCNV2 retinopathy: clinical features, molecular genetics and directions for future therapy.Semantic proximity Read ↗

Mutations in the gene KCNV2 encoding a voltage-gated potassium channel subunit cause "cone dystrophy with supernormal rod electroretinogram" in humans.Semantic proximity Read ↗

Establishment and comprehensive characterization of a novel dark-reared zebrafish model for myopia studiesSemantic proximity Read ↗

Establishment and comprehensive characterization of a novel dark-reared zebrafish model for myopia studiesSemantic proximity Read ↗

The electroretinogram in the genomics era: outer retinal disorders.Semantic proximity Read ↗

Deficiency of the neurodevelopmental disorder-associated geneCyfip2alters the retinal ganglion cell properties and visual acuitySemantic proximity Read ↗

Myopia-26, the female-limited form of early-onset high myopia, occurring in a European familySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.