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Article

Genetic Spectrum of Negative Electroretinograms in a Predominantly Pediatric Cohort of 177 Patients.

Investigative ophthalmology & visual science - 1 Dec 2025

Zaslavsky Kirill, Tumber Anupreet, Millar Eoghan, Boginskaia Olga, MacDonald Heather, Klatt Regan, Ali Asim, Heon Elise, Vincent Ajoy

Abstract excerpt

Purpose: The purpose of this study was to elucidate the common and rare genetic causes of negative electroretinograms (nERGs) and their association with systemic disease and with myopia in a predominantly pediatric cohort. Methods: Patients underwent electroretinogram (ERG) testing at the Hospital for Sick Children (Toronto) between 2007 and 2023. Negative ERG was defined as b/a amplitude of <1 to a dark-adapted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41342616
DOI: 10.1167/iovs.66.15.19
PMCID: PMC12697691

Genes

CACNA1F
ERG
ABHD12
AP3B2
IDUA
NYX
OAT
PCDH15
PDE6A
RS1
TRPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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