Article
Evaluation of serum haptoglobin levels and Hp1-Hp2 polymorphism in the haptoglobin gene in patients with atrial fibrillation.
Molecular biology reports - 1 Aug 2022
Costa Luana Bernardes Xavier, Martins Gabriela Lopes, Duarte Rita Carolina Figueiredo, Rocha Pâmella Lemos, Figueiredo Estêvão Lanna, Silveira Francisco Rezende, das Graças Carvalho Maria, Reis Helton José, Gomes Karina Braga, Ferreira Cláudia Natália
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is an arrhythmia that involves structural and electrophysiological abnormalities. Many of the AF-related clinical conditions are associated with an increase in inflammatory and oxidative factors. Haptoglobin (Hp) is an acute phase protein whose biological role is to promote clearance of free hemoglobin (Hb). In addition, for being considered an inflammatory marker, Hp...
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