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A Randomized Controlled Phase 3 Study on the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Idiopathic Short Stature

29 Apr 2022

Abstract excerpt

Background To evaluate the safety and efficacy of daily somatropin (Jintropin®), a recombinant human growth hormone, in prepubertal children with ISS in China. Methods This study was a multicenter, randomized, controlled, open-label, phase 3 study. All subjects were randomized 3:1 to daily somatropin 0.05 mg/kg/day or no treatment for 52 weeks. A total of 481 subjects with a mean baseline age of 5.8 years were...

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PMID: 35573994
DOI: 10.3389/fendo.2022.864908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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