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A Novel Y-Shaped Pegylated Recombinant Human Growth Hormone for Children With Growth Hormone Deficiency

27 Nov 2024

Abstract excerpt

CONTEXT: Pegpesen is a novel Y-shape pegylated recombinant human growth hormone (rhGH) for once-weekly treatment of children with growth hormone deficiency (GHD). OBJECTIVE: This work aimed to evaluate the efficacy and safety of Pegpesen in children with GHD vs daily rhGH. METHODS: A multicenter, randomized, controlled phase 3 clinical trial was conducted at 23 centers in China with a duration of 52 weeks'...

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PMID: 39607675
DOI: 10.1210/clinem/dgae816

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