Article
Robust Antibody and T Cell Responses to SARS-CoV-2 in Patients with Antibody Deficiency.
Journal of clinical immunology - 1 Aug 2021
Kinoshita Hannah, Durkee-Shock Jessica, Jensen-Wachspress Mariah, Kankate Vaishnavi V, Lang Haili, Lazarski Christopher A, Keswani Anjeni, Webber Kathleen C, Montgomery-Recht Kimberly, Walkiewicz Magdalena, Notarangelo Luigi D, Burbelo Peter D, Fuss Ivan, Cohen Jeffrey I, Bollard Catherine M, Keller Michael D
Abstract excerpt
Immunocompromised patients, including those with inborn errors of immunity (IEI), may be at increased risk for severe or prolonged infections with SARS-CoV-2 (Zhu et al. N Engl J Med. 382:727-33, 2020; Guan et al. 2020; Minotti et al. J Infect. 81:e61-6, 2020). While antibody and T cell responses to SARS-CoV-2 structural proteins are well described in healthy convalescent donors, adaptive humoral and cellular...
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