Article
Expression of BMP4 and FOXN1 in orthokeratinized odontogenic cyst compared to odontogenic keratocyst suggests an epidermal phenotype.
Biotechnic & histochemistry : official publication of the Biological Stain Commission - 1 Nov 2022
Thermos Grigorios, Piperi Evangelia, Tosios Konstantinos I, Nikitakis Nikolaos G
Abstract excerpt
Odontogenic keratocysts (OKC) and orthokeratinized odontogenic cysts (OOC) are odontogenic cysts that share histological and immunohistochemical similarity with epidermal appendages and cutaneous cystic lesions despite exhibiting contrasting biological behavior. In epidermal appendages, BMP4 induces expression of FOXN1, which participates in terminal differentiation of keratinocytes and control of proliferation....
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