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Differentially expressed extracellular matrix genes functionally separate ameloblastoma from odontogenic keratocyst

13 Sept 2024

Abstract excerpt

BACKGROUND: Ameloblastoma and odontogenic keratocyst (OKC) are odontogenic tumors that develop from remnants of odontogenic epithelium. Both display locally invasive growth characteristics and high predilection for recurrence after surgical removal. Most ameloblastomas harbor BRAFV600E mutation while OKCs are associated with PATCH1 gene mutation but distinctive indicators of ameloblastoma growth characteristics...

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PMID: 39272104
DOI: 10.1186/s12903-024-04866-7

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